Pore size and filtration rate relationship

Physio Ex Activity 1 Cell Transport Mechanisms and Permeability Essay Example for Free

pore size and filtration rate relationship

The filtration method used in the study was a standard glass funnel and base with vacuum Table 1. Test Filters. Pore Size Millipore. Flow Rate. Bubble Point. Typical. (µm) filter code (sec/ relation to filter pore size. Six different filter pore. concentration increases, and diffusion rate increases as solute molecular weight decreases Pore size increased filtration rate because, as pore size increases. MF (microfiltration) – Pore size generally spans micron to 1 micron, the relation between the gas permeation rate and the TMP, pore size.

Put the following in order from smallest to largest molecular weight: Sodium Chloride, Urea, Glucose, and Albumin.

Bio 135 Anatomy and Physiology

Simulated Facilitated Diffusion 1. Explain one way in which facilitated diffusion is the same as simple diffusion and one way in which it is different from simple diffusion.

pore size and filtration rate relationship

Facilitated diffusion is the same as simple diffusion in that they are both passive and go down or with the concentration gradient. It is different from simple diffusion in that facilitated diffusion uses a carrier protein to transport it across the membrane. The larger value obtained when more glucose carriers were present corresponds to an increase in the rate of glucose transport.

Explain why the rate increased. The rate of glucose that was transported increased because when the concentration of glucose got higher, so the rate of diffusion went up.

Through Pore Size Characterization of Filtration Materials - Filtration News

When there is a higher concentration gradient the rate of diffusion increases, so the more glucose carriers made it easier for the glucose to diffuse more quickly though the membrane. In other words, explain why you picked the choice that you did. We predicted that the glucose transport rate would increase. Our results matched our prediction. Simulating Osmotic Pressure 1.

Describe one way in which osmosis is similar to simple diffusion and one way in which it is different.

Water Movement in Soil

Osmosis is similar to simple diffusion in that it is a passive diffusion and moves down the concentration gradient. It is different because Osmosis takes place when there is a difference in concentration gradient across a selectively permeable membrane.

Solutes are sometimes measured in milliosmoles. Water moves though most membranes easily and moves when there is a change in water concentration between two sides of membrane; meaning that water is chasing the concentration gradient.

pore size and filtration rate relationship

The conditions were 9 mM albumin in the left beaker and 10 mM glucose in the right beaker with the MWCO membrane in place. The osmotic pressure for both was L. Even with a high osmotic pressure albumin was still unable to pass though the MWCO membrane. We predicted that with a higher osmotic pressure both would diffuse though the membrane, but glucose was the one molecule that was able to diffuse through the membrane.

NF can effectively remove divalent ions at relatively high efficiency, e. The high chemical potential imposed by the high pressure in feed side dissolves water into the membrane material followed by water desorption from the permeate side where chemical potential is low.

As a result the solubility of molecules in membrane material plays a major role in rejection efficiency in addition to the sieving mechanisms.

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For instance, the rejection efficiency of lithium ions 6. It is mainly because lithium ions becomes very unstable when they are dissolved in membrane materials due to the charge repulsion enhanced by the low electric permittivity of membrane material. On the other hand, since ethanol molecules do not have net charge, they do not experience high repulsions among others when they are dissolved in membrane materials.

This suggests that as soon as ions dissolved in membrane materials, repulsion among ions increases around Due to the stronger destabilization of divalent ions in membrane materials, rejection efficiencies of divalent ions are much higher than those of monovalent ions.

Rejection efficiencies of small organics without charge such as methanol, ethanol, propanol, acetone, etc.

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A few theoretical models exist to describe the phenomena and are described here. Classification of membrane filtration as a function of molecular weight cut off and pore size Koch Membrane Systems. MF and UF typically run at low pressure, e.

The following diagram shows the solutes that are rejected by each membrane.

pore size and filtration rate relationship

As discussed hereregardless of the membrane pore size, actual solute sizes rejected by MF and UF are approximately same since the cake layer formed on membrane surface acts as a dynamic membrane in actual filtration process.

However, tiny molecules with low molecular weight perhaps less than a few tens of thousand Dalton can be better rejected by UF than by MF regardless of the existence of dynamic membrane.

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NF branes and RO membranes are used to remove trace organic molecules and ions in water filtration.