Blood Pressure in Relation to Age and Frailty
The definition of normal BP (systolic blood pressure [SBP] relationship between age and DBP is a straight line in. purpose. To describe the cross-sectional relationships between age, blood pressure (BP), and quantitative measures of retinal vessel diameters in an older. comparisons between these groups have not produced consistent findings of the relationship between blood pressure variability and age. In this paper we report.
Identification of Normal Blood Pressure in Different Age Group
Furthermore, by using logistic splines analytic method, Port et al 6 also suggested that hypertension should be defined according to age- and sex-specific threshold rather than a single value. The clustering of hypertension, dyslipidemia, and obesity have been noted early in It should be stressed that the original purpose to define MetS was trying to early detect subjects with high risk for CVD and diabetes.
Till now, compiling results derived either in the cross-sectional or the longitudinal studies all repeatedly validated its predictability. It is not difficult to postulate that these endpoints are common in the elderly. However, in the younger cohort, these cardiovascular outcomes are much less to be found.
Relation between change of blood pressure and age.
To have enough number for an observational study to become statistically significant would take a long time which is difficult for many of the researchers. Unfortunately, the aforementioned definition for normotension derived from older cohort is being applied to all age groups at present, and it is easily to understand that this is just not reasonable. Ever since the publication of the notion of MetS, there are many longitudinal studies focusing on its predictable CVD.
Thus, MetS could be used as a surrogate to replace the actual cardiovascular outcomes in the younger subjects. Although it is less accurate, by using this method, we could re-evaluate the more logical cutoff points of normotension in the younger population. Therefore, we hypothesized that the definition for normal SBP and DBP should vary rather than using the same value in all age-groups. In this cross-sectional study, we enrolledsubjects. The levels of BP calculated from these curves could detect either CVD or diabetes more precisely and should be regarded as the definition of hypertension in its corresponding age and sex groups.
Finally, these equations are further verified and compared with the present standard of normal BP in the remaining one fifths of the subjects. MJ health screening centers are privately owned chain of outpatient department located throughout the whole Taiwan, which offer routine health checkups.
Therefore, the database contained subjects everywhere in Taiwan. All study subjects were anonymous, and informed consent was obtained from each participant. The study proposal was reviewed by the institutional review board of MJ Health Screening. Totally,subjects were enrolled when undergoing routine health checkups.
Relation between change of blood pressure and age.
They were between 21 and 65 years old. Since BP was the major variables we evaluated in this study, subjects who taking any medications would influence BP were excluded. Finally,63, men and 64, women were eligible for the analysis. Four fifths of them were randomly selected as the study group and the other one fifths as the validation group. Anthropometric Measurements and General Data The participant's medical history, including present medications, was acquired by the study nurses using a questionnaire.
Detailed physical examinations were done for each subject. Waist circumference was measured at the midpoint between the inferior border of the last rib and the iliac crest in a horizontal level.
A computerized auto-mercury-sphygmomanometer, Citizen CH Citizen, Tokyo, Japan was used to measure BP on the right arm of each subject seated, after 5 minutes of rest.
BP was measured twice at min intervals. The average value of these 2 records was taken into the analysis. Laboratory Evaluation After the 10 hour overnight fast, blood specimens were collected from each subject for further analysis.
Fasting plasma glucose FPG and plasma lipid concentrations were measured later. An enzymatic cholesterol assay following dextran sulfate precipitation was used to determine serum high-density lipoprotein cholesterol and low-density lipoprotein cholesterol levels.
In the present study, the BP was the independent component.Hypertension Striking the Young
Thus, subjects with any 2 of remaining 4 MetS components were regarded as fulfilling the diagnosis of MetS. We used a prospective cohort study design with 53, men followed for cause-specific death during a median of 5.
Baseline age, systolic BP and diastolic BP were collected. There were CVD deaths during follow-up. In this large cohort of healthy men with no history of hypertension, systolic BP was the most consistent and significant predictor of CVD death across all ages. Diastolic BP was not as strongly associated with risk. Our results support the continuing emphasis on using systolic BP in predicting cardiovascular risk. Blood pressureage groupscardiovascular diseasesprospective studies Hypertension is a risk factor for cardiovascular disease CVD1 and the risk associated with elevated blood pressures BP may be affected by age.
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In andletters were sent toUS male physicians on the American Medical Association mailing list that included an invitation to participate in the trial, informed consent forms, and a questionnaire to provide baseline information. By the end of, physicians had responded to the mailing and returned an initial enrollment questionnaire.
Our study evaluated the 53, respondents aged 39 to 85 years who provided self-reported BP, had no past or current treatment for hypertension, and had no history of myocardial infarction MIstroke, cancer, transient ischemic attack TIAgout, peptic ulcer, or liver disease. Body mass index in kilograms per meters squared was calculated using weight and height.
Using the National Death Index indeath certificates were obtained for the respondents who died before the end of The deaths were classified by trained nosologists using the first revision of the Ninth International Classification of Diseases in conjunction with the Automated Classification of Medical Entities Decision Tables to manually select underlying cause of death. Statistical Analysis Analyses were stratified a priori by age at baseline as 39 to 49, 50 to 59, 60 to 69, and 70 to 84 years.