Difference Between Antigen and Pathogen | Difference Between | Antigen vs Pathogen
Basic introduction to antigens & pathogens. Antigens & Pathogens. Mr. Rahilly. Loading Unsubscribe from Mr. Rahilly? Cancel. Pathogen refers to an (foreign) agent that causes disease. So, virus/bacteria/ parasite but not all of them. A commensal organism that just hangs out in your. The precise relationship between memory cells and those of the primary immune . a concave relationship between pathogen virulence and immune stimulation . Hence, the more vigorous the virus's replication rate, the more antigens are.
Antibodies have three main functions: They neutralize the pathogen, activate other defense cells and activate the complement system. Neutralization Neutralizing pathogens or changed cells is one of the most important tasks of antibodies.
Difference between Antigen and Pathogen
To do this, they attach directly to the surface of a virus or bacterium and stop the pathogen from attaching itself to a normal body cell and infecting it.
Or the antibody binds to toxins produced by bacteria. These substances can then no longer enter the body cells and damage them. Activating many defense cells Antibodies can activate many different defense cells, which are in the blood, the lymph fluid and the tissue. These include scavenger cells phagocytes in the tissue, blood platelets thrombocytes in the blood and mast cells, which are responsible for many allergic reactions.
Scavenger cells, for example, can fight pathogens a lot better if they are packed with antibodies all around them. The scavenger cells can take in the germs better and faster, to digest them in the inside of the cell.
Activating the complement system Antibodies are also capable of activating various other proteins that enhance the defense reaction. The proteins of the complement system have different effects: They can directly damage the cell walls of pathogens, widen blood vessels and support inflammatory reaction.
Many proteins of the complement system can also attract defense cells to the site of the infection and activate scavenger cells, which then dissolve and destroy the germs.
Forms of antibodies There are different forms of antibodies in the body. They can be grouped in five classes. These antibodies are produced mostly towards the end of a new infection. They are responsible for effectively fighting pathogens that are already known.
They can both activate the complement system and mark pathogens by attaching all around the germ and thus making it palatable to the scavenger cells.
In pregnant women, IgG antibodies can be passed on from the mother to the unborn child. This protects the child in the first time after birth from the most important pathogens, until its own immune system has become more mature. In the first line: IgM antibodies IgM antibodies are very big molecules and are capable of making infected cells lump together quickly. When a pathogen is identified, these are the first antibodies to be produced in order to quickly stop the pathogen from spreading.
IgM antibodies are also responsible for incompatibility reactions between different blood groups. In people with the blood group A, for example, antibodies in the blood fluid would immediately attack blood cells from people with blood group B and make them lump together. IgA antibodies IgA antibodies are the specialists found in all body fluids like saliva, or mucus in the bronchi or the bowel.
They help to defend against germs locally in the typical entry sites like the mouth, lungs or bowel.
Some of them are also found in the blood. IgE antibodies IgE antibodies play an important role in defending against infections of parasites like worms, for example.
They are also responsible for many allergic reactions. They attach to mast cells, a special sub-form of white blood cells. Mast cells are responsible for typical allergic symptoms like reddening and hives on the skin, allergic rhinitis or asthma -like breathing difficulties.
IgD antibodies The function of this class of antibodies is not yet fully known. IgD antibodies are found on the surface of B cells and can also bind to pathogens, so that these can be destroyed by other defense cells. Messenger substances of the immune system Besides defense cells, many soluble substances also contribute to the elimination of pathogens. These substances are mainly proteins, for example inflammatory proteins or hormone-like messenger substances in the tissue — so-called cytokines.
The defense cells use cytokines to communicate with one another or with other body cells and thus make sure that infected or cancerous cells are recognized and eliminated. Cytokines are released by many cells of the immune system and they themselves activate many other cells or stimulate them to grow and to mature. Interleukins, interferons and tumor-necrosis factor are some of the best-known cytokines.
Scavenger cells, T and B cells and connective tissue cells of the skin are some of the cells that produce interleukins.
By stimulating the multiplication of defense cells and connective tissue cells, interleukins support wound healing. They are also responsible for inducing fever and can attract other immune cells in the tissue.
Other functions of interleukins are stimulating T cells to multiply and increasing antibody production in B cells. Cells that have been infected by a virus release interferons in order to protect neighboring cells from the virus. The neighboring cells bind interferons to their surface, which makes them less susceptible to the virus.
The defense mechanisms of the adaptive immune system - Informed Health Online - NCBI Bookshelf
One of the special functions of the so-called tumor necrosis factor is to destroy cancerous body cells. Interferons are now used as medications, for example in the treatment of some rare forms of leukemia cancer of the blood and in different types of viral inflammation of the liver. If the immune system is weakened by another disease, they are also used for protection against infections.
I believe that you might have noticed the words pathogen and antigen in the previous paragraphs. Some of you might have already discerned the difference between the two, while others may be a little bit confused. But do not worry because I will explain the differences between the two.
A pathogen is any foreign organism not a part of the body that invades or is present inside the body, mainly in the bloodstream. A pathogen is also something that causes harm to the body and affects normal functioning.
Simply speaking, it is an agent that causes a disease to its host. Examples would be bacteria, virus, or fungi. On the other hand, an antigen is short for antibody generator.
It is not an organism, but rather, a molecule attached to a foreign organism that activates an antibody response.
- Specialists at work: T helper cells and T killer cells
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This means that an antigen triggers the response of different antibodies depending on its match, like a lock-and-key. Usually, antigens are located in the cell walls of bacteria, or in the outer coating of other foreign organisms.
Antigen vs Pathogen - Difference Between
You can read more about this since only basic details are provided here. Our immune system protects us from foreign organisms or pathogens that can cause diseases. A pathogen is a harmful organism that can cause a disease to its host.